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Graduate School of Biomedical Sciences

Tony Lin

M.D./Ph.D. Student

Tony Lin is a graduate student in the (MD/PhD Program) studying APOBEC mutagenesis under the mentorship of Reuben Harris, D.Phil. For his research, Tony is studying the post-translational regulation of a cytidine deaminase called APOBEC3B and its role in cancer mutagenesis. For his clinical specialty, Tony is considering pursuing pathology or radiology.

About Me

Born and raised in Taiwan. Lived in Vermont and California growing up. Got a BA in Molecular and Cell Biology from UC Berkeley. Was told to pursue my dreams so started trying things out after college. Enrolled in Chabot College in Hayward, CA to compete in tennis at the collegiate level in hopes of going professional. Realized a year in that no one will ever pay to watch me play. Hung up my racquet (figuratively speaking since I still play) and moved on to a research gig in the Wiita lab at UCSF. Loved it and was getting paid so thought I was on the right track. Now back in school to pursue science and medicine.

Hobbies/Interests

Tennis, stand-up comedy, wrangling data

Research Topic

DNA-mutating enzymes in cancer, DNA damage response, multi-omics data integration

Why I chose MD/PhD

I see myself going into academic medicine in the future. My goal is to teach and conduct research in hopes of improving patient care and human health. Pursuing an MD/PhD is a small step toward that.

Why I chose MD/PhD at º£½ÇÂ×ÂÒ

The unique interview process (i.e. chalk talk), supportive and transparent leadership, and a friendly student body stood out to me.

Post-bac work or other affiliations

Junior Specialist at University of California San Francisco 

Education

B.A., Molecular and Cell Biology, University of California Berkeley, 2015

Publications

Paranjape N, Lin YT, Flores-Ramirez Q, Sarin V, Johnson AB, Chu J, Paredes M, Wiita AP. (2022). . BioRxiv.

Ferguson ID, Lin YT, Lam C, Shao H, Tharp KM, Hale M, Kasap C, Mariano MC, Kishishita A, Escobar BP, Mandal K, Steri V, Wang D, Phojanakong P, Tuomivaara ST, Hann B, Driessen C, Van Ness B, Gestwicki JE, Wiita AP. (2022). . Cell Chemical Biology. In press.

Solvik TA, Nguyen TA, Lin YT, Marsh T, Huang EJ, Wiita AP, Debnath J, Leidal AM. (2022). . Journal of Cell Biology. 221(6):e202110151.

Liu JY, Lin YT, Leidal AM, Huang HH, Ye J, Wiita AP, Debnath J. (2021). . Biology Open. 10(10):bio058736.

Nix MA, Mandal K. Geng H, Paranjape N, Lin YT, Rivera J, Marcoulis M, White KL, Whitman J, Bapat SP, Parker KR, Ramirez J, Deucher A, Phojanokong P, Steri V, Fattahi F, Hann B, Satpathy AT, Manglik A, Stieglitz E, Wiita AP. (2021). . Cancer Discovery. 11(8):2032-2049.

Huang HH, Ferguson ID, Thornton AM, Lam CY, Lin YT, Bastola P, Choudhry P, Mariano MC, Marcoulis MD, Malato J, Phojanakong P, Martin TG, Wolf JL, Wong SW, Shah N, Hann BC, Brooks AN, Wiita AP. (2020). . Nat Comm. 11(1):1931.

Guo X, Aviles G, Liu Y, Tian R, Unger BA, Lin YT, Wiita AP, Xu K, Correia MA, Kampmann M. (2020). . Nature. 579(7799):427-432.

Lin YT, Way GP, Barwick BG, Mariano MC, Marcoulis M, Ferguson ID, Driessen C, Boise LH, Greene CS, Wiita AP. (2019). . Blood Advances. 3(21):3214-3227.

Crottès D, Lin YT, Peters CJ, Gilchrist JM, Wiita AP, Jan YN, Jan LY. (2019). . PNAS. 116(26):13026-13035.

Lam C, Ferguson ID, Mariano MC, Lin YT, Murnane M, Liu H, Smith GA, Wong SW, Taunton J, Liu JO, Mitsiades CS, Hann BC, Aftab BT, Wiita AP. (2018). . Haematologica. 103(7):1218-1228.

Goode B, Mondal G, Hyun M, Ruiz DG, Lin YT, Van Ziffle J, Joseph NM, Onodera C, Talevich E, Grenert JP, Hewedi IH, Snuderl M, Brat DJ, Kleinschmidt-DeMasters BK, Rodriguez FJ, Louis DN, Yong WH, Lopes MB, Rosenblum MK, Butowski N, Tihan T, Bollen AW, Phillips JJ, Wiita AP, Yeh I, Jacobson MP, Bastian BC, Perry A, Solomon DA. (2018). . Nat Comm. 9(1):810.

Lin YT, Huang CV, Ho C, Shatsky M, Kirsch JF. (2017). . BioRxiv.